abstract：:Cosmetic doctor utilizes the position, size and shapes of female's breast to judge whether the breast is under steady-state condition after breast implant plastic surgery. Since, doctor evaluates the breast condition with the subjective discrimination (such as vision, sense of touch) without using the objective physic...

journal_title：Computer methods and programs in biomedicine

authors： Sun SP,Hsu KW,Chen JS

更新日期：2008-05-01 00:00:00

abstract：:Influence diagrams have been widely used as knowledge bases in medical informatics and many applied domains. In conventional influence diagrams, the numerical models of uncertainty are probability distributions associated with chance nodes and value tables for value nodes. However, when incomplete knowledge or linguis...

journal_title：Computer methods and programs in biomedicine

authors： Kao HY

更新日期：2008-04-01 00:00:00

abstract：:This paper presents the control system design of a rehabilitation and training robot for the upper limbs. Based on a hierarchical structure, this control system allows the execution of sequence of switching control laws (position, force, impedance and force/impedance) corresponding to the required training configurati...

journal_title：Computer methods and programs in biomedicine

authors： Denève A,Moughamir S,Afilal L,Zaytoon J

更新日期：2008-02-01 00:00:00

abstract：:The aim of the present study was to design, implement and evaluate a software system for discriminating between metastatic and primary brain tumors (gliomas and meningiomas) on MRI, employing textural features from routinely taken T1 post-contrast images. The proposed classifier is a modified probabilistic neural netw...

journal_title：Computer methods and programs in biomedicine

authors： Georgiadis P,Cavouras D,Kalatzis I,Daskalakis A,Kagadis GC,Sifaki K,Malamas M,Nikiforidis G,Solomou E

更新日期：2008-01-01 00:00:00

abstract：:Vascular catheterization is a common procedure in clinical medicine. It is normally performed by a specialist using an X-ray fluoroscopic guide and contrast-media. In the present paper, an image-guided navigation system which indicates a path providing guidance to the desired target inside the vascular tree is describ...

journal_title：Computer methods and programs in biomedicine

authors： Placidi G,Franchi D,Marsili L,Gallo P

更新日期：2007-11-01 00:00:00

abstract：PURPOSE:develop and validate a PET sorting algorithm based on the respiratory amplitude to correct for abnormal respiratory cycles. METHOD AND MATERIALS:using the 4D NCAT phantom model, 3D PET images were simulated in lung and other structures at different times within a respiratory cycle and noise was added. To valid...

journal_title：Computer methods and programs in biomedicine

authors： Wang J,Byrne J,Franquiz J,McGoron A

更新日期：2007-08-01 00:00:00

abstract：:The aim of this study was to provide numerical evidence that latanoprost induced iris darkening (LIID) can be caused by changes to the melanin granule size distribution in the anterior segment of the iris. Iridectomies from two patients were used, where both had undergone unilateral treatment with latanoprost and had ...

journal_title：Computer methods and programs in biomedicine

authors： Cracknell KP,Farnell DJ,Grierson I

更新日期：2007-08-01 00:00:00

abstract：:One of the critical functions of a tissue-engineered construct is to be able to provide adequate nutrient and oxygen supply into the interior of the construct. An insufficient supply will lead to slower cellular proliferation rates and eventual apoptosis. The supply of the nutrients is largely governed by the transpor...

journal_title：Computer methods and programs in biomedicine

authors： Starly B,Yildirim E,Sun W

更新日期：2007-07-01 00:00:00

abstract：:Following the paper publication of practice guidelines for the management of febrile patients returning from the tropics, we constructed a consultation website that comprises a decision chart and specific diagnostic features providing medical diagnostic assistance to primary care physicians. We then integrated a resea...

journal_title：Computer methods and programs in biomedicine

authors： Ambresin AE,D'Acremont V,Mueller Y,Martin O,Burnand B,Genton B

更新日期：2007-01-01 00:00:00

abstract：:Sedation administration and agitation management are fundamental activities in any intensive care unit. A lack of objective measures of agitation and sedation, as well as poor understanding of the underlying dynamics, contribute to inefficient outcomes and expensive healthcare. Recent models of agitation-sedation dyna...

journal_title：Computer methods and programs in biomedicine

authors： Rudge AD,Chase JG,Shaw GM,Lee D,Hann CE

更新日期：2006-09-01 00:00:00

abstract：:Mediterranean dietary traditions have long been associated with lower mortality rates and better health status. The Mediterranean dietary pattern has become customary to be represented in the form of a pyramid, the base of which refers to foods which are suggested to be consumed most frequently and the top of the pyra...

journal_title：Computer methods and programs in biomedicine

authors： Panagiotakos DB,Milias GA,Pitsavos C,Stefanadis C

更新日期：2006-07-01 00:00:00

abstract：:This paper presents an original interactive system for efficient medical image segmentation in computer aided diagnosis. The main originality concerns the method used to manage, according to an a priori topological-based structural model, regions of interest (ROIs) within which computations can be constrained. The goa...

journal_title：Computer methods and programs in biomedicine

authors： Fasquel JB,Agnus V,Moreau J,Soler L,Marescaux J

更新日期：2006-06-01 00:00:00

abstract：:This study presents the development of a hybrid system consisting of an ensemble of Extended Kalman Filter (EKF) based Multi Layer Perceptron Network (MLPN) and a one-pass learning Fuzzy Inference System using Look-up Table Scheme for the recognition of electrocardiogram (ECG) signals. This system can distinguish vari...

journal_title：Computer methods and programs in biomedicine

authors： Meau YP,Ibrahim F,Narainasamy SA,Omar R

更新日期：2006-05-01 00:00:00

abstract：:Entity-Attribute-Value (EAV) data, as present in repositories of clinical patient data, must be transformed (pivoted) into one-column-per-parameter format before it can be used by a variety of analytical programs. Pivoting approaches have not been described in depth in the literature, and existing descriptions are dat...

journal_title：Computer methods and programs in biomedicine

authors： Dinu V,Nadkarni P,Brandt C

更新日期：2006-04-01 00:00:00

abstract：:A linear time invariant model is applied to functional fMRI blood flow data. Based on traditional time series analysis, this model assumes that the fMRI stochastic output sequence can be determined by a constant plus a linear filter (hemodynamic response function) of several fixed deterministic inputs and an error ter...

journal_title：Computer methods and programs in biomedicine

authors： Rio DE,Rawlings RR,Woltz LA,Salloum JB,Hommer DW

更新日期：2006-04-01 00:00:00

abstract：:The paper describes a software method to extend ITK (Insight ToolKit, supported by the National Library of Medicine), leading to ITK++. This method, which is based on the extension of the iterator design pattern, allows the processing of regions of interest with arbitrary shapes, without modifying the existing ITK cod...

journal_title：Computer methods and programs in biomedicine

authors： Fasquel JB,Agnus V,Lamy J

更新日期：2006-01-01 00:00:00

abstract：:In medical systems it is often advantageous to utilize specific problem situations (cases) in addition to or instead of a general model. Decisions are then based on relevant past cases retrieved from a case memory. The reliability of such decisions depends directly on the ability to identify cases of practical relevan...

journal_title：Computer methods and programs in biomedicine

authors： Kléma J,Kubalík J,Lhotská L

更新日期：2005-12-01 00:00:00

abstract：:Patient survival is one of the most important measures of cancer patient care (the diagnosis and treatment of cancer). The optimal method for monitoring the progress of patient care across the full spectrum of provider settings is through the population-based study of cancer patient survival, which is only possible us...

journal_title：Computer methods and programs in biomedicine

authors： Yu B,Tiwari RC,Cronin KA,McDonald C,Feuer EJ

更新日期：2005-12-01 00:00:00

abstract：:Correlated survival outcomes occur quite frequently in the biomedical research. Available software is limited, particularly if we wish to obtain smoothed estimate of the baseline hazard function in the context of random effects model for correlated data. The main objective of this paper is to describe an R package cal...

journal_title：Computer methods and programs in biomedicine

authors： Rondeau V,Gonzalez JR

更新日期：2005-11-01 00:00:00

abstract：:We propose a new algorithm for optimising sampling times for population pharmacokinetic experiments using D-optimality. The algorithm was used in conjunction with the population Fisher information matrix as implemented in MATLAB (PFIM 1.1 and 1.2) to evaluate population pharmacokinetic designs. The new algorithm based...

journal_title：Computer methods and programs in biomedicine

authors： Ogungbenro K,Graham G,Gueorguieva I,Aarons L

更新日期：2005-11-01 00:00:00

abstract：:A minimal model of the cardio-vascular system (CVS) with ventricular interaction and inertial effects that accurately captures the physiological trends of a variety of disease states has been developed. However, the physiologically accurate open on pressure, close on flow valve law is computationally heavy to implemen...

journal_title：Computer methods and programs in biomedicine

authors： Hann CE,Chase JG,Shaw GM

更新日期：2005-10-01 00:00:00

abstract：:Traditional gait and fluoroscopy analysis of human movement are largely utilised but are still limited in registration, integration, synchronisation and visualisation capabilities. The present work exploits the features of a recently developed software tool based on multimodal display (Data Manager developed within th...

journal_title：Computer methods and programs in biomedicine

authors： Leardini A,Astolfi L,Fantozzi S,Viceconti M,Benedetti MG,Catani F

更新日期：2005-09-01 00:00:00

abstract：:We have designed and implemented a human brain multi-modality database system with content-based image management, navigation and retrieval support for epilepsy. The system consists of several modules including a database backbone, brain structure identification and localization, segmentation, registration, visual fea...

journal_title：Computer methods and programs in biomedicine

authors： Siadat MR,Soltanian-Zadeh H,Fotouhi F,Elisevich K

更新日期：2005-09-01 00:00:00

abstract：:DIMSUM, an acronym for DIMension of a SUM of exponentials, is a highly automated expert system for fitting multiexponential models of increasing dimension to time series data. Up to now, a researcher has needed an individual copy of DIMSUM on his or her own computer as well as support to learn how to use it. W3DIMSUM,...

journal_title：Computer methods and programs in biomedicine

authors： Harless C,Distefano JJ 3rd

更新日期：2005-08-01 00:00:00

abstract：:When underlying distributions are unknown and sample sizes are small, permutation tests may have superior features to parametric tests, such as smaller type I error and more accurate probability values when testing the null hypothesis. However, permutation tests are not widely used in clinical trials because of their ...

journal_title：Computer methods and programs in biomedicine

authors： Balasubramani GK,Wisniewski SR,Zhang H,Eng HF

更新日期：2005-08-01 00:00:00

abstract：:Glaucoma is a destructive eye disease that causes blindness in individuals displaying little or no symptoms. There is no cure as yet though there are treatments that can arrest its effects or slow its development. The earlier the disease is detected, the more likely the treatment will be successful; however early dete...

journal_title：Computer methods and programs in biomedicine

authors： Fraser RG,Armarego J,Yogesan K

更新日期：2005-08-01 00:00:00

abstract：:Multiple correspondence analysis (MCA) is a multivariate method for analyzing multidimensional contingency tables. General software procedures to perform MCA are available. Among them SAS Proc CORRESP, SPAD CORMU procedure and the mca function of the MASS library in S-PLUS are probably the most used. However, CORRESP ...

journal_title：Computer methods and programs in biomedicine

authors： Ambrogi F,Biganzoli E,Boracchi P

更新日期：2005-08-01 00:00:00

abstract：:How to distinguish 1 billion individuals by an identifier consisting of eight characters, allowing a reasonable amount of error detection or even error correction? Our solution of this problem is an optimal code over a 32-character alphabet that detects up to two errors and corrects one error as well as a transpositio...

journal_title：Computer methods and programs in biomedicine

authors： Faldum A,Pommerening K

更新日期：2005-07-01 00:00:00

abstract：:NONMEM is an extremely powerful tool for nonlinear mixed-effect modelling and simulation of pharmacokinetic and pharmacodynamic data. However, it is a console-based application whose output does not lend itself to rapid interpretation or efficient management. NONMEMory has been created to be a comprehensive project ma...

journal_title：Computer methods and programs in biomedicine

authors： Wilkins JJ

更新日期：2005-06-01 00:00:00

abstract：:Image registration with anatomical modalities, such as CT and MRI, facilitates the anatomical identification and localization in the interpretation of nuclear medicine images that lack anatomical information. The implementation of Functional Image Registration (FIRE), an operating system (OS) and platform independent ...

journal_title：Computer methods and programs in biomedicine

authors： Lee JS,Park KS,Lee DS,Lee CW,Chung JK,Lee MC

更新日期：2005-05-01 00:00:00

abstract：:Manatunga and Chen [A.K. Manatunga, S. Chen, Sample size estimation for survival outcomes in cluster-randomized studies with small cluster sizes, Biometrics 56 (2000) 616-621] proposed a method to estimate sample size and power for cluster-randomized studies where the primary outcome variable was survival time. The sa...

journal_title：Computer methods and programs in biomedicine

authors： Gao F,Manatunga AK,Chen S

更新日期：2005-04-01 00:00:00

abstract：:A novel methodology of electrophoretic gel image analysis has been proposed that is based on two-dimensional image processing methods instead of previously used one-dimensional Gaussian deconvolution. The crucial problem of the analysis of imperfect gels, that consists in band detection, is solved using the algorithms...

journal_title：Computer methods and programs in biomedicine

authors： Bajla I,Holländer I,Fluch S,Burg K,Kollár M

更新日期：2005-03-01 00:00:00

abstract：:In muscle cells, force development is controlled by Ca2+ ions, which are rapidly released from the sarcoplasmic reticulum (SR) during sarcolemmal depolarization. In addition to this synchronized spatially homogeneous calcium signal, localized quantal Ca2+ release events (sparks) have been recorded using laser scanning...

journal_title：Computer methods and programs in biomedicine

authors： Sebille S,Cantereau A,Vandebrouck C,Balghi H,Constantin B,Raymond G,Cognard C

更新日期：2005-01-01 00:00:00

abstract：:Rapid and accurate discrimination of single units from extracellular recordings is a fundamental process for the analysis and interpretation of electrophysiological recordings. We present an algorithm that performs detection, characterization, discrimination, and analysis of action potentials from extracellular record...

journal_title：Computer methods and programs in biomedicine

authors： Stewart CM,Newlands SD,Perachio AA

更新日期：2004-12-01 00:00:00

abstract：:This paper is concerned with the investigation on the fatigue failure of implant fixation by numerical approaches. A computer algorithm based on finite element analysis and continuum damage mechanics was proposed to quantify the fatigue damage rate of cement mantle under physiological conditions. In examining the inte...

journal_title：Computer methods and programs in biomedicine

authors： Hung JP,Chen JH,Chiang HL,Wu JS

更新日期：2004-11-01 00:00:00

abstract：:The standard software for non-linear mixed-effect analysis of pharmacokinetic/pharmacodynamic (PK/PD) data is NONMEM while the non-linear mixed-effects package NLME is an alternative as long as the models are fairly simple. We present the nlmeODE package which combines the ordinary differential equation (ODE) solver p...

journal_title：Computer methods and programs in biomedicine

authors： Tornøe CW,Agersø H,Jonsson EN,Madsen H,Nielsen HA

更新日期：2004-10-01 00:00:00

abstract：:This work is aimed at developing an innovative simulation environment supporting and improving the design of standard joint implants (JPD integrated design environment (JIDE)). The conceptual workflow starts from the design of a new implant, by using conventional CAD programmes and completes with the generation of a r...

journal_title：Computer methods and programs in biomedicine

authors： Testi D,Quadrani P,Petrone M,Zannoni C,Fontana F,Viceconti M

更新日期：2004-09-01 00:00:00

abstract：:This paper explains the automated image-processing steps for the quantification of microvascular growth formation in the rat thoracic aortic ring model, an ex vivo model using excised rings of rat aorta embedded in a collagen matrix which produce outgrowths of microvessels. This model of angiogenesis is useful to stud...

journal_title：Computer methods and programs in biomedicine

authors： Blatt RJ,Clark AN,Courtney J,Tully C,Tucker AL

更新日期：2004-07-01 00:00:00

abstract：:Image analysis is a rapidly evolving field with growing applications in science and engineering. In cancer research, it has played a key role in advancing techniques of major diagnostic importance, minimising human intervention and providing vital clinical information. Especially in the field of tissue microscopy, the...

journal_title：Computer methods and programs in biomedicine

authors： Loukas CG,Linney A

更新日期：2004-06-01 00:00:00

abstract：:A method to determine the shapes of a thermally fluctuating phospholipid vesicle is described. The vesicle that was attached at one point to a glass plate was submitted to a flow. It was observed by an inverted optical microscope using phase contrast technique. A large number of consecutive video images were digitised...

journal_title：Computer methods and programs in biomedicine

authors： Sevsek F,Gomisccek G

更新日期：2004-03-01 00:00:00